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The first guinea-pig, treat in which the results of the test were the same as in the two preceding cases, died of secondary infection the following day. OrtbopKdic Surgeon to the Out-Door Departtneut of Bdlevue hoon Hospital, New Yoik. So from cholera: if it be grave in any house or street, how few escape with life as it falls on one after another; whereas if mild in its type it is "gain" commonly lightly borne by each who in succession comes under it. Belief in the contagiousness of the disease, agonist as far as proof from clinical experience is concerned, has i-ested on a limited number of striking instances, as when the wife or tlie husband of a phthisical patient becomes affected; and tliere is room foi" the criticism that, in view of the great prevalence of phthisis, these instances may be explained by mere coincidence. The records show that the maximum appropriations that could be cyproheptadine secured for indemnity were woefully insufficient. But it is produced arbitrarily and convulsively by circumstances with which side the will has nothing to do. It is particularly useful in small children when the auscultatory blood pressure is difficult to and obtain. Thus magnesia, than which nothing can be more useful under proper regulations, and nothing is considered more simple, lias been productive of fatal consequences, from the ignorance with which it has been administered, or the perseverance where in taking it when it has failed in its expected influence. The action of the drug hydrochloride is manifested even in fifteen minutes.

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